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Effects and translatomics characteristics of a small-molecule inhibitor of METTL3 against non-small cell lung cancer

In non-small cell lung cancer (NSCLC), the heterogeneity promotes drug resistance, and the restricted expression of programmed death-ligand 1 (PD-L1) limits the immunotherapy benefits. Based on the mechanisms related to translation regulation and the association with PD-L1 of methyltransferase-like...

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Detalles Bibliográficos
Autores principales: Xiao, Han, Zhao, Rong, Meng, Wangyang, Liao, Yongde
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10334285/
https://www.ncbi.nlm.nih.gov/pubmed/37440912
http://dx.doi.org/10.1016/j.jpha.2023.04.009