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Small molecule inhibitors of RORγt for Th17 regulation in inflammatory and autoimmune diseases

As a ligand-dependent transcription factor, retinoid-associated orphan receptor γt (RORγt) that controls T helper (Th) 17 cell differentiation and interleukin (IL)-17 expression plays a critical role in the progression of several inflammatory and autoimmune conditions. An emerging novel approach to...

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Detalles Bibliográficos
Autores principales: Zeng, Jiuping, Li, Mingxing, Zhao, Qianyun, Chen, Meijuan, Zhao, Long, Wei, Shulin, Yang, Huan, Zhao, Yueshui, Wang, Anqi, Shen, Jing, Du, Fukuan, Chen, Yu, Deng, Shuai, Wang, Fang, Zhang, Zhuo, Li, Zhi, Wang, Tiangang, Wang, Shengpeng, Xiao, Zhangang, Wu, Xu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10334362/
https://www.ncbi.nlm.nih.gov/pubmed/37440911
http://dx.doi.org/10.1016/j.jpha.2023.05.009