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Mutational landscape of SWI/SNF complex genes reveal correlation to predictive biomarkers for immunotherapy sensitivity in lung adenocarcinoma patients

BACKGROUND: The search for prognostic biomarkers indicating sensitivity to immunotherapy in lung adenocarcinoma patients has zeroed in on genes in the switch/sucrose non-fermentable (SWI/SNF) pathway. The mutational profiles of key genes are not clearly defined, however, and no comparisons have been...

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Detalles Bibliográficos
Autores principales: Xu, H., Chen, H.-C., Yang, L., Yang, G., Liang, L., Yang, Y., Tang, H., Bao, H., Wu, X., Shao, Y., An, G., Wang, Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10334452/
https://www.ncbi.nlm.nih.gov/pubmed/37327699
http://dx.doi.org/10.1016/j.esmoop.2023.101585