Cargando…

Tumor-targeted dual-action NSAID-platinum(iv) anticancer prodrugs

Platinum(iv) prodrugs are a promising class of anticancer agents designed to overcome the limitations of conventional platinum(ii) therapeutics. In this work, we present oxaliplatin(iv)-based complexes, which upon reduction, release acetylsalicylic acid (aspirin), known for its antitumor activity ag...

Descripción completa

Detalles Bibliográficos
Autores principales: Kastner, Alexander, Mendrina, Theresa, Bachmann, Florian, Berger, Walter, Keppler, Bernhard K., Heffeter, Petra, Kowol, Christian R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10334471/
https://www.ncbi.nlm.nih.gov/pubmed/37440920
http://dx.doi.org/10.1039/d3qi00968h