Dexmedetomidine ameliorates diabetic cardiomyopathy by inhibiting ferroptosis through the Nrf2/GPX4 pathway

OBJECTIVE: Dexmedetomidine (DEX) has been shown to have anti-apoptotic effects in diabetes mellitus, but its role in mitigating diabetic cardiomyopathy (DCM) through ferroptosis regulation is unclear. METHODS: An in vitro DCM model was established using H9C2 cells induced with high glucose (HG) and...

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Detalles Bibliográficos
Autores principales: Li, Fan, Hu, Zhenfei, Huang, Yidan, Zhan, Haiting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10334540/
https://www.ncbi.nlm.nih.gov/pubmed/37430319
http://dx.doi.org/10.1186/s13019-023-02300-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10334540/
https://www.ncbi.nlm.nih.gov/pubmed/37430319
http://dx.doi.org/10.1186/s13019-023-02300-7

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