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Impaired angiogenesis in ageing: the central role of the extracellular matrix

Each step in angiogenesis is regulated by the extracellular matrix (ECM). Accumulating evidence indicates that ageing-related changes in the ECM driven by cellular senescence lead to a reduction in neovascularisation, reduced microvascular density, and an increased risk of tissue ischaemic injury. T...

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Detalles Bibliográficos
Autores principales: Xiao, Ping, Zhang, Yanli, Zeng, Yuting, Yang, Dehong, Mo, Jiayao, Zheng, Ziting, Wang, Jilei, Zhang, Yuxin, Zhou, Zhiyan, Zhong, Xincen, Yan, Wenjuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10334673/
https://www.ncbi.nlm.nih.gov/pubmed/37434156
http://dx.doi.org/10.1186/s12967-023-04315-z