The RNA-binding proteins hnRNP H and F regulate splicing of a MYC-dependent HRAS exon in prostate cancer cells

The MYC proto-oncogene contributes to the pathogenesis of more than half of human cancers. Malignant transformation by MYC transcriptionally up-regulates the core pre-mRNA splicing machinery and causes misregulation of alternative splicing. However, our understanding of how splicing changes are dire...

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Detalles Bibliográficos
Autores principales: Chen, Xinyuan, Yang, Harry Taegyun, Zhang, Beatrice, Phillips, John W., Cheng, Donghui, Rigo, Frank, Witte, Owen N., Xing, Yi, Black, Douglas L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10334793/
https://www.ncbi.nlm.nih.gov/pubmed/37399401
http://dx.doi.org/10.1073/pnas.2220190120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10334793/
https://www.ncbi.nlm.nih.gov/pubmed/37399401
http://dx.doi.org/10.1073/pnas.2220190120

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