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The RNA-binding proteins hnRNP H and F regulate splicing of a MYC-dependent HRAS exon in prostate cancer cells

The MYC proto-oncogene contributes to the pathogenesis of more than half of human cancers. Malignant transformation by MYC transcriptionally up-regulates the core pre-mRNA splicing machinery and causes misregulation of alternative splicing. However, our understanding of how splicing changes are dire...

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Detalles Bibliográficos
Autores principales:	Chen, Xinyuan, Yang, Harry Taegyun, Zhang, Beatrice, Phillips, John W., Cheng, Donghui, Rigo, Frank, Witte, Owen N., Xing, Yi, Black, Douglas L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2023
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10334793/ https://www.ncbi.nlm.nih.gov/pubmed/37399401 http://dx.doi.org/10.1073/pnas.2220190120

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