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Forces and energetics of the canonical tetrameric cation channel gating

The canonical gating mechanism of tetrameric cation channels involves the spreading of the pore-lining helices at the so-called bundle-crossing gate. Despite a wealth of structural information, we lack a physical description of the gating process. Here, I took advantage of an entropic polymer stretc...

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Detalles Bibliográficos
Autor principal: Scheuring, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10334803/
https://www.ncbi.nlm.nih.gov/pubmed/37399394
http://dx.doi.org/10.1073/pnas.2221616120