Hepatocyte HSPA12A inhibits macrophage chemotaxis and activation to attenuate liver ischemia/reperfusion injury via suppressing glycolysis-mediated HMGB1 lactylation and secretion of hepatocytes

Rationale: Liver ischemia-reperfusion (LI/R) injury is characterized by two interconnected phases: local ischemia that causes hepatic cell damage to release damage-associated molecular pattern (DAMPs), and DAMPs that recruit immune cells to elicit inflammatory cascade for further injury of hepatocyt...

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Detalles Bibliográficos
Autores principales: Du, Shuya, Zhang, Xiaojin, Jia, Yunxiao, Peng, Peipei, Kong, Qiuyue, Jiang, Surong, Li, Yuehua, Li, Chuanfu, Ding, Zhengnian, Liu, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10334822/
https://www.ncbi.nlm.nih.gov/pubmed/37441587
http://dx.doi.org/10.7150/thno.82607

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10334822/
https://www.ncbi.nlm.nih.gov/pubmed/37441587
http://dx.doi.org/10.7150/thno.82607

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