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Hepatocyte HSPA12A inhibits macrophage chemotaxis and activation to attenuate liver ischemia/reperfusion injury via suppressing glycolysis-mediated HMGB1 lactylation and secretion of hepatocytes
Rationale: Liver ischemia-reperfusion (LI/R) injury is characterized by two interconnected phases: local ischemia that causes hepatic cell damage to release damage-associated molecular pattern (DAMPs), and DAMPs that recruit immune cells to elicit inflammatory cascade for further injury of hepatocyt...
Autores principales: | Du, Shuya, Zhang, Xiaojin, Jia, Yunxiao, Peng, Peipei, Kong, Qiuyue, Jiang, Surong, Li, Yuehua, Li, Chuanfu, Ding, Zhengnian, Liu, Li |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10334822/ https://www.ncbi.nlm.nih.gov/pubmed/37441587 http://dx.doi.org/10.7150/thno.82607 |
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