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RNF157 attenuates CD4(+) T cell-mediated autoimmune response by promoting HDAC1 ubiquitination and degradation
Background: CD4(+) T cells play an important role in body development and homeostasis. Quantitative and functional changes in CD4(+) T cells result in abnormal immune responses, which lead to inflammation, cancer, or autoimmune diseases, such as multiple sclerosis (MS). Ubiquitination plays an essen...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10334825/ https://www.ncbi.nlm.nih.gov/pubmed/37441600 http://dx.doi.org/10.7150/thno.86307 |