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RNF157 attenuates CD4(+) T cell-mediated autoimmune response by promoting HDAC1 ubiquitination and degradation

Background: CD4(+) T cells play an important role in body development and homeostasis. Quantitative and functional changes in CD4(+) T cells result in abnormal immune responses, which lead to inflammation, cancer, or autoimmune diseases, such as multiple sclerosis (MS). Ubiquitination plays an essen...

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Detalles Bibliográficos
Autores principales: Wang, Peng, Zhao, Jingjing, Tan, Yunke, Sheng, Junli, He, Shitong, Chen, Yitian, Nie, Dingnai, You, Xiaolong, Luo, Jinmei, Zhang, Yanling, Hu, Shengfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10334825/
https://www.ncbi.nlm.nih.gov/pubmed/37441600
http://dx.doi.org/10.7150/thno.86307