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The HDAC10 instructs macrophage M2 program via deacetylation of STAT3 and promotes allergic airway inflammation

Background: Perturbation of macrophage homeostasis is one of the key mechanisms of airway inflammation in asthma. However, the exact mechanisms remain poorly understood. Objectives: We sought to examine the role of histone deacetylase (HDAC) 10 as an epigenetic regulator that governs macrophage M2 p...

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Detalles Bibliográficos
Autores principales: Zhong, Yu, Huang, Tong, Huang, Jiewen, Quan, Jingyun, Su, Guomei, Xiong, Zhilin, Lv, Yingying, Li, Shihai, Lai, Xianwen, Xiang, Yuanyuan, Wang, Qu, Luo, Lianxiang, Gao, Xiao, Shao, Yiming, Tang, Jing, Lai, Tianwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10334828/
https://www.ncbi.nlm.nih.gov/pubmed/37441601
http://dx.doi.org/10.7150/thno.82535