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Single-cell RNA sequencing identifies critical transcription factors of tumor cell invasion induced by hypoxia microenvironment in glioblastoma

Rationale: Glioblastoma (GBM) is an aggressive malignant primary brain cancer with poor survival. Hypoxia is a hallmark of GBM, which promotes tumor cells spreading (invasion) into the healthy brain tissue. Methods: To better elucidate the influence of hypoxia on GBM invasion, we proposed a data-dri...

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Detalles Bibliográficos
Autores principales: Zhang, Yanru, Zhang, Bo, Lv, Chengqian, Zhang, Nan, Xing, Kaiyuan, Wang, Zixuan, Lv, Rongkai, Yu, Mingchen, Xu, Chaohan, Wang, Yihan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10334835/
https://www.ncbi.nlm.nih.gov/pubmed/37441593
http://dx.doi.org/10.7150/thno.81407