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Therapeutic silencing of lncRNA RMST alleviates cardiac fibrosis and improves heart function after myocardial infarction in mice and swine

Rationale: Cardiac fibrosis is an adverse consequence of aberrant fibroblast activation and extracellular matrix (ECM) deposition following myocardial infarction (MI). Recently, long noncoding RNAs (lncRNAs) have been reported to participate in multiple cardiac diseases. However, the biological func...

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Detalles Bibliográficos
Autores principales: Ma, Teng, Qiu, Fan, Gong, Yanshan, Cao, Hao, Dai, Gonghua, Sun, Daohan, Zhu, Dongling, Lei, Han, Liu, Zhongmin, Gao, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10334841/
https://www.ncbi.nlm.nih.gov/pubmed/37441584
http://dx.doi.org/10.7150/thno.82543