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PFKFB3 downregulation aggravates Angiotensin II-induced podocyte detachment

Podocytes play a critical role in maintaining normal glomerular filtration, and podocyte loss from the glomerular basement membrane (GBM) initiates and worsens chronic kidney disease (CKD). However, the exact mechanism underlying podocyte loss remains unclear. Fructose-2,6-biphosphatase 3 (PFKFB3) i...

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Detalles Bibliográficos
Autores principales: Huang, Xiaoxiao, Chen, Zhaowei, Luo, Zilv, Hao, Yiqun, Feng, Jun, Zhu, Zijing, Yang, Xueyan, Zhang, Zongwei, Hu, Jijia, Liang, Wei, Ding, Guohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10334864/
https://www.ncbi.nlm.nih.gov/pubmed/37427767
http://dx.doi.org/10.1080/0886022X.2023.2230318