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MLL methyltransferases regulate H3K4 methylation to ensure CENP-A assembly at human centromeres
The active state of centromeres is epigenetically defined by the presence of CENP-A interspersed with histone H3 nucleosomes. While the importance of dimethylation of H3K4 for centromeric transcription has been highlighted in various studies, the identity of the enzyme(s) depositing these marks on t...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10335677/ https://www.ncbi.nlm.nih.gov/pubmed/37379335 http://dx.doi.org/10.1371/journal.pbio.3002161 |