HPV E6 inhibits E6AP to regulate epithelial homeostasis by modulating keratinocyte differentiation commitment and YAP1 activation

Human papillomaviruses (HPV) cause persistent infections by modulating epithelial homeostasis in cells of the infected basal layer. Using FUCCI and cell-cell competition assays, we have identifed regulatory roles for E6AP and NHERF1, which are the primary HPV11 E6 cellular targets, as well as being...

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Detalles Bibliográficos
Autores principales: Yin, Wen, Egawa, Nagayasu, Zheng, Ke, Griffin, Heather, Tian, Pu, Aiyenuro, Ademola, Bornstein, Jacob, Doorbar, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10335691/
https://www.ncbi.nlm.nih.gov/pubmed/37379354
http://dx.doi.org/10.1371/journal.ppat.1011464

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10335691/
https://www.ncbi.nlm.nih.gov/pubmed/37379354
http://dx.doi.org/10.1371/journal.ppat.1011464

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