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Dermokine mutations contribute to epithelial-mesenchymal transition and advanced melanoma through ERK/MAPK pathways

To discover vulnerabilities associated with dermokine (DMKN) as a new trigger of the epithelial-mesenchymal transition (EMT) -driven melanoma, we undertook a genome-wide genetic screening using transgenic. Here, we showed that DMKN expression could be constitutively increased in human malignant mela...

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Detalles Bibliográficos
Autores principales: Ma, Wenqiong, Wu, Zexiu, Maghsoudloo, Mazaher, Ijaz, Iqra, Dehghan Shasaltaneh, Marzieh, Zhang, Yuqin, Weng, Qiao, Fu, Junjiang, Imani, Saber, Wen, Qing Lian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10335698/
https://www.ncbi.nlm.nih.gov/pubmed/37432950
http://dx.doi.org/10.1371/journal.pone.0285806