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Defibrotide modulates pulmonary endothelial cell activation and protects against lung inflammation in pre-clinical models of LPS-induced lung injury and idiopathic pneumonia syndrome

INTRODUCTION: A multiple organ dysfunction syndrome (MODS) workshop convened by the National Institute of Child Health and Human Development in 2015 identified acute respiratory distress syndrome (ARDS) and complications of allogeneic blood and marrow transplantation (allo-BMT) as contributors to MO...

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Detalles Bibliográficos
Autores principales: Klein, Orly R., Ktena, Yiouli P., Pierce, Elizabeth, Fu, Han-Hsuan, Haile, Azeb, Liu, Chen, Cooke, Kenneth R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10335747/
https://www.ncbi.nlm.nih.gov/pubmed/37441074
http://dx.doi.org/10.3389/fimmu.2023.1186422