Sequential and directional insulation by conserved CTCF sites underlies the Hox timer in stembryos

During development, Hox genes are temporally activated according to their relative positions on their clusters, contributing to the proper identities of structures along the rostrocaudal axis. To understand the mechanism underlying this Hox timer, we used mouse embryonic stem cell-derived stembryos....

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Detalles Bibliográficos
Autores principales: Rekaik, Hocine, Lopez-Delisle, Lucille, Hintermann, Aurélie, Mascrez, Bénédicte, Bochaton, Célia, Mayran, Alexandre, Duboule, Denis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10335938/
https://www.ncbi.nlm.nih.gov/pubmed/37322110
http://dx.doi.org/10.1038/s41588-023-01426-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10335938/
https://www.ncbi.nlm.nih.gov/pubmed/37322110
http://dx.doi.org/10.1038/s41588-023-01426-7

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