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Limited choice of natural amino acids as mimetics restricts design of protein lysine methylation studies

Protein lysine methylation plays important biological roles but its experimental characterization is limited by the lack of suitable mimetics of methylated and unmethylated lysine among the natural amino acids. Here, we summarize the consequent challenges and discuss alternative approaches for bioch...

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Detalles Bibliográficos
Autores principales: Weirich, Sara, Jeltsch, Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10336004/
https://www.ncbi.nlm.nih.gov/pubmed/37433789
http://dx.doi.org/10.1038/s41467-023-39777-8