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YF17D-vectored Ebola vaccine candidate protects mice against lethal surrogate Ebola and yellow fever virus challenge

Ebola virus (EBOV) and related filoviruses such as Sudan virus (SUDV) threaten global public health. Effective filovirus vaccines are available only for EBOV, yet restricted to emergency use considering a high reactogenicity and demanding logistics. Here we present YF-EBO, a live YF17D-vectored dual...

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Detalles Bibliográficos
Autores principales: Lemmens, Viktor, Kelchtermans, Lara, Debaveye, Sarah, Chiu, Winston, Vercruysse, Thomas, Ma, Ji, Thibaut, Hendrik Jan, Neyts, Johan, Sanchez-Felipe, Lorena, Dallmeier, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10336040/
https://www.ncbi.nlm.nih.gov/pubmed/37433816
http://dx.doi.org/10.1038/s41541-023-00699-7