The Sherpa hypothesis: Phenotype-Preserving Disordered Proteins stabilize the phenotypes of neurons and oligodendrocytes

Intrinsically disordered proteins (IDPs), which can interact with many partner proteins, are central to many physiological functions and to various pathologies that include neurodegeneration. Here, we introduce the Sherpa hypothesis, according to which a subset of stable IDPs that we term Phenotype-...

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Detalles Bibliográficos
Autores principales: Norris, Vic, Oláh, Judit, Krylov, Sergey N., Uversky, Vladimir N., Ovádi, Judit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10336114/
https://www.ncbi.nlm.nih.gov/pubmed/37433867
http://dx.doi.org/10.1038/s41540-023-00291-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10336114/
https://www.ncbi.nlm.nih.gov/pubmed/37433867
http://dx.doi.org/10.1038/s41540-023-00291-8

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