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Reduced slow-wave activity and autonomic dysfunction during sleep precede cognitive deficits in Alzheimer’s disease transgenic mice

Occurrence of amyloid-β (Aβ) aggregation in brain begins before the clinical onset of Alzheimer’s disease (AD), as preclinical AD. Studies have reported that sleep problems and autonomic dysfunction associate closely with AD. However, whether they, especially the interaction between sleep and autono...

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Detalles Bibliográficos
Autores principales: Chen, Chieh-Wen, Kwok, Yam-Ting, Cheng, Yu-Ting, Huang, Yu-Shan, Kuo, Terry B. J., Wu, Cheng-Han, Du, Pei-Jing, Yang, Albert C., Yang, Cheryl C. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10336117/
https://www.ncbi.nlm.nih.gov/pubmed/37433857
http://dx.doi.org/10.1038/s41598-023-38214-6