Spatial cellular architecture predicts prognosis in glioblastoma

Intra-tumoral heterogeneity and cell-state plasticity are key drivers for the therapeutic resistance of glioblastoma. Here, we investigate the association between spatial cellular organization and glioblastoma prognosis. Leveraging single-cell RNA-seq and spatial transcriptomics data, we develop a d...

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Detalles Bibliográficos
Autores principales: Zheng, Yuanning, Carrillo-Perez, Francisco, Pizurica, Marija, Heiland, Dieter Henrik, Gevaert, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10336135/
https://www.ncbi.nlm.nih.gov/pubmed/37433817
http://dx.doi.org/10.1038/s41467-023-39933-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10336135/
https://www.ncbi.nlm.nih.gov/pubmed/37433817
http://dx.doi.org/10.1038/s41467-023-39933-0

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