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Multi-batch single-cell comparative atlas construction by deep learning disentanglement

Cell state atlases constructed through single-cell RNA-seq and ATAC-seq analysis are powerful tools for analyzing the effects of genetic and drug treatment-induced perturbations on complex cell systems. Comparative analysis of such atlases can yield new insights into cell state and trajectory altera...

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Detalles Bibliográficos
Autores principales: Lynch, Allen W., Brown, Myles, Meyer, Clifford A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10336139/
https://www.ncbi.nlm.nih.gov/pubmed/37433791
http://dx.doi.org/10.1038/s41467-023-39494-2