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Upregulation of endocytic protein expression in the Alzheimer’s disease male human brain

Amyloid-beta (Aβ) is produced from amyloid precursor protein (APP) primarily after APP is internalised by endocytosis and clathrin-mediated endocytic processes are altered in Alzheimer’s disease (AD). There is also evidence that cholesterol and flotillin affect APP endocytosis. We hypothesised that...

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Detalles Bibliográficos
Autores principales: Alsaqati, Mouhamed, Thomas, Rhian S., Kidd, Emma J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10336166/
https://www.ncbi.nlm.nih.gov/pubmed/37449017
http://dx.doi.org/10.1016/j.nbas.2023.100084