Cargando…

Upregulation of endocytic protein expression in the Alzheimer’s disease male human brain

Amyloid-beta (Aβ) is produced from amyloid precursor protein (APP) primarily after APP is internalised by endocytosis and clathrin-mediated endocytic processes are altered in Alzheimer’s disease (AD). There is also evidence that cholesterol and flotillin affect APP endocytosis. We hypothesised that...

Descripción completa

Detalles Bibliográficos
Autores principales:	Alsaqati, Mouhamed, Thomas, Rhian S., Kidd, Emma J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10336166/ https://www.ncbi.nlm.nih.gov/pubmed/37449017 http://dx.doi.org/10.1016/j.nbas.2023.100084

Ejemplares similares

Decreasing the expression of PICALM reduces endocytosis and the activity of β-secretase: implications for Alzheimer’s disease
por: Thomas, Rhian S., et al.
Publicado: (2016)

Pharmacological intervention to restore connectivity deficits of neuronal networks derived from ASD patient iPSC with a TSC2 mutation
por: Alsaqati, Mouhamed, et al.
Publicado: (2020)

Reply to Peng and Zhao: Loss of endocytic protein TOM1 in Alzheimer’s disease
por: Martini, Alessandra C., et al.
Publicado: (2020)

Protein Expression of Angiotensin-Converting Enzyme 2 (ACE2) is Upregulated in Brains with Alzheimer’s Disease
por: Ding, Qiyue, et al.
Publicado: (2021)

Numb Is an Endocytic Protein
por: Santolini, Elisa, et al.
Publicado: (2000)

A high ratio of linoleic acid (n-6 PUFA) to alpha-linolenic acid (n-3 PUFA) adversely affects early stage of human neuronal differentiation and electrophysiological activity of glutamatergic neurons in vitro
por: Dec, Karolina, et al.
Publicado: (2023)

Upregulation of calpain activity precedes tau phosphorylation and loss of synaptic proteins in Alzheimer’s disease brain
por: Kurbatskaya, Ksenia, et al.
Publicado: (2016)

Nucleocytoplasmic Shuttling of Endocytic Proteins
por: Vecchi, Manuela, et al.
Publicado: (2001)

The protein architecture of the endocytic coat analyzed by FRET microscopy
por: Skruzny, Michal, et al.
Publicado: (2020)

Endocytic Adaptors in Cardiovascular Disease
por: Cui, Kui, et al.
Publicado: (2020)

Antimicrobial peptide β-defensin-1 expression is upregulated in Alzheimer’s brain
por: Williams, Wesley M, et al.
Publicado: (2013)

Regional protein expression in human Alzheimer’s brain correlates with disease severity
por: Xu, Jingshu, et al.
Publicado: (2019)

Endocytic Adaptor Proteins in Health and Disease: Lessons from Model Organisms and Human Mutations
por: Azarnia Tehran, Domenico, et al.
Publicado: (2019)

Protein farnesylation is upregulated in Alzheimer’s human brains and neuron-specific suppression of farnesyltransferase mitigates pathogenic processes in Alzheimer’s model mice
por: Jeong, Angela, et al.
Publicado: (2021)

Rare variants in the endocytic pathway are associated with Alzheimer’s disease, its related phenotypes, and functional consequences
por: Zhan, Lingyu, et al.
Publicado: (2021)

Panax notoginsenoside Rb1 ameliorates Alzheimer’s disease by upregulating brain-derived neurotrophic factor and downregulating Tau protein expression
por: WANG, YU, et al.
Publicado: (2013)

Impaired Caveolae Function and Upregulation of Alternative Endocytic Pathways Induced by Experimental Modulation of Intersectin-1s Expression in Mouse Lung Endothelium
por: Predescu, Dan N., et al.
Publicado: (2012)

Upregulation of extracellular proteins in a mouse model of Alzheimer’s disease
por: Kim, Sangkyu, et al.
Publicado: (2023)

The endocytic recycling regulator EHD1 is essential for spermatogenesis and male fertility in mice
por: Rainey, Mark A, et al.
Publicado: (2010)

Co-Expression Analysis of microRNAs and Proteins in Brain of Alzheimer’s Disease Patients
por: Watson, Callum N., et al.
Publicado: (2022)

Papillomaviruses and Endocytic Trafficking
por: Siddiqa, Abida, et al.
Publicado: (2018)

Angiotensin-converting enzyme 2 (ACE2) is upregulated in Alzheimer’s disease brain
por: Ding, Qiyue, et al.
Publicado: (2020)

Systematic spatial mapping of proteins at exocytic and endocytic structures
por: Larson, Ben T., et al.
Publicado: (2014)

Ca(2+)-Sensor Proteins in the Autophagic and Endocytic Traffic
por: Ghislat, Ghita, et al.
Publicado: (2013)

Subversion of the Endocytic and Secretory Pathways by Bacterial Effector Proteins
por: Weber, Mary M., et al.
Publicado: (2018)

Fusion accessibility of endocytic compartments along the recycling and lysosomal endocytic pathways in intact cells
Publicado: (1989)

Atlas of RNA editing events affecting protein expression in aged and Alzheimer’s disease human brain tissue
por: Ma, Yiyi, et al.
Publicado: (2021)

An Aberrant Phosphorylation of Amyloid Precursor Protein Tyrosine Regulates Its Trafficking and the Binding to the Clathrin Endocytic Complex in Neural Stem Cells of Alzheimer's Disease Patients
por: Poulsen, Ebbe T., et al.
Publicado: (2017)

Yeast Eps15-like endocytic protein Pan1p regulates the interaction between endocytic vesicles, endosomes and the actin cytoskeleton
por: Toshima, Junko Y, et al.
Publicado: (2016)

Neuron-Glia Interactions Increase Neuronal Phenotypes in Tuberous Sclerosis Complex Patient iPSC-Derived Models
por: G. Nadadhur, Aishwarya, et al.
Publicado: (2018)

Measuring Plasma Membrane Protein Endocytic Rates by Reversible Biotinylation
por: Gabriel, Luke, et al.
Publicado: (2009)

Endocytic Adaptor Protein Tollip Inhibits Canonical Wnt Signaling
por: Toruń, Anna, et al.
Publicado: (2015)

Liquid-like protein interactions catalyze assembly of endocytic vesicles
por: Day, Kasey J., et al.
Publicado: (2021)

Quantitative visualization of endocytic trafficking through photoactivation of fluorescent proteins
por: Ecker, Manuela, et al.
Publicado: (2021)

Taking apart the endocytic machinery
por: Kaksonen, Marko
Publicado: (2008)

The endocytic activity of dendritic cells
Publicado: (1995)

A Screen for Endocytic Motifs
por: Kozik, Patrycja, et al.
Publicado: (2010)

DNA Demethylation Upregulated Nrf2 Expression in Alzheimer’s Disease Cellular Model
por: Cao, Huimin, et al.
Publicado: (2016)

Author Correction: Upregulation of extracellular proteins in a mouse model of Alzheimer’s disease
por: Kim, Sangkyu, et al.
Publicado: (2023)

The antimicrobial protein, CAP37, is upregulated in pyramidal neurons during Alzheimer’s disease
por: Brock, Amanda J., et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_8va9btgo9kvqjlr23gejasulvb