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Wavelet coherence phase analysis decodes the universal switching mechanism of Ras GTPase superfamily
The Ras superfamily of GTPases regulate critical cellular processes by shuttling between GTP-bound ON and GDP-bound OFF states. This switching mechanism is attributed to the conformational changes in two loops, SWI and SWII, upon GTP binding and hydrolysis. Since these conformational changes vary ac...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10336170/ https://www.ncbi.nlm.nih.gov/pubmed/37448564 http://dx.doi.org/10.1016/j.isci.2023.107031 |