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The right time to measure anti-Xa activity in critical illness: pharmacokinetics of therapeutic dose nadroparin

BACKGROUND: Peak anti-Xa activity of low-molecular-weight heparin nadroparin is measured 3 to 5 hours after subcutaneous injection. In critically ill patients, physiological changes and medical therapies may result in peak activities before or after this interval, possibly impacting dosing. OBJECTIV...

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Detalles Bibliográficos
Autores principales: Sytema, Jelmer G., Loef, Bert G., Loovers, Harriët M., Boer, Marijn, Touw, Daniël J., van Hulst, Marinus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10336191/
https://www.ncbi.nlm.nih.gov/pubmed/37449055
http://dx.doi.org/10.1016/j.rpth.2023.100185