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The right time to measure anti-Xa activity in critical illness: pharmacokinetics of therapeutic dose nadroparin
BACKGROUND: Peak anti-Xa activity of low-molecular-weight heparin nadroparin is measured 3 to 5 hours after subcutaneous injection. In critically ill patients, physiological changes and medical therapies may result in peak activities before or after this interval, possibly impacting dosing. OBJECTIV...
Autores principales: | Sytema, Jelmer G., Loef, Bert G., Loovers, Harriët M., Boer, Marijn, Touw, Daniël J., van Hulst, Marinus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10336191/ https://www.ncbi.nlm.nih.gov/pubmed/37449055 http://dx.doi.org/10.1016/j.rpth.2023.100185 |
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