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Genetic insight into the putative causal proteins and druggable targets of osteoporosis: a large-scale proteome-wide mendelian randomization study

Background: Osteoporosis is a major causative factor of the global burden of disease and disability, characterized by low bone mineral density (BMD) and high risks of fracture. We aimed to identify putative causal proteins and druggable targets of osteoporosis. Methods: This study utilized the large...

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Detalles Bibliográficos
Autores principales: Wu, Zhichong, Yang, Kenneth Guangpu, Lam, Tsz-Ping, Cheng, Jack Chun Yiu, Zhu, Zezhang, Lee, Wayne Yuk-Wai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10336211/
https://www.ncbi.nlm.nih.gov/pubmed/37448626
http://dx.doi.org/10.3389/fgene.2023.1161817