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TSG101 Physically Interacts with Linear Ubiquitin Chain Assembly Complex (LUBAC) and Upregulates the TNFα-Induced NF-κB Activation

Linear ubiquitin chain assembly complex (LUBAC) is a ubiquitin E3 ligase complex composed of HOIP, HOIL-1L, and SHARPIN that catalyzes the formation of linear/M1-linked ubiquitin chain. It has been shown to play a pivotal role in the nuclear factor (NF)-κB signaling induced by proinflammatory stimul...

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Detalles Bibliográficos
Autores principales: Kim, Eunju, Cho, Hyunchu, Lee, Gaeul, Baek, Heawon, Lee, In Young, Choi, Eui-Ju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10336271/
https://www.ncbi.nlm.nih.gov/pubmed/37431163
http://dx.doi.org/10.14348/molcells.2023.0026