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The Bcl-2/Bcl-xL Inhibitor ABT-263 Attenuates Retinal Degeneration by Selectively Inducing Apoptosis in Senescent Retinal Pigment Epithelial Cells

Age-related macular degeneration (AMD) is one of the leading causes of blindness in elderly individuals. However, the currently used intravitreal injections of anti-vascular endothelial growth factor are invasive, and repetitive injections are also accompanied by a risk of intraocular infection. The...

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Detalles Bibliográficos
Autores principales: Ryu, Wonseon, Park, Chul-Woo, Kim, Junghoon, Lee, Hyungwoo, Chung, Hyewon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10336274/
https://www.ncbi.nlm.nih.gov/pubmed/37222160
http://dx.doi.org/10.14348/molcells.2023.2188