A method for polyclonal antigen-specific T cell-targeted genome editing (TarGET) for adoptive cell transfer applications

Adoptive cell therapy of donor-derived, antigen-specific T cells expressing native T cell receptors (TCRs) is a powerful strategy to fight viral infections in immunocompromised patients. Determining the fate of T cells following patient infusion hinges on the ability to track them in vivo. While thi...

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Detalles Bibliográficos
Autores principales: Palianina, Darya, Di Roberto, Raphaël B., Castellanos-Rueda, Rocío, Schlatter, Fabrice, Reddy, Sai T., Khanna, Nina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10336339/
https://www.ncbi.nlm.nih.gov/pubmed/37448595
http://dx.doi.org/10.1016/j.omtm.2023.06.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10336339/
https://www.ncbi.nlm.nih.gov/pubmed/37448595
http://dx.doi.org/10.1016/j.omtm.2023.06.007

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