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A method for polyclonal antigen-specific T cell-targeted genome editing (TarGET) for adoptive cell transfer applications
Adoptive cell therapy of donor-derived, antigen-specific T cells expressing native T cell receptors (TCRs) is a powerful strategy to fight viral infections in immunocompromised patients. Determining the fate of T cells following patient infusion hinges on the ability to track them in vivo. While thi...
Autores principales: | Palianina, Darya, Di Roberto, Raphaël B., Castellanos-Rueda, Rocío, Schlatter, Fabrice, Reddy, Sai T., Khanna, Nina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10336339/ https://www.ncbi.nlm.nih.gov/pubmed/37448595 http://dx.doi.org/10.1016/j.omtm.2023.06.007 |
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