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Role of innate immunity and systemic inflammation in cystic fibrosis disease progression

Pathophysiological manifestations of cystic fibrosis (CF) result from a functional defect in the cystic fibrosis transmembrane conductance regulator (CFTR) paving way for mucus obstruction and pathogen colonization. The role of CFTR in modulating immune cell function and vascular integrity, irrespec...

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Detalles Bibliográficos
Autores principales: Purushothaman, Anand Kumar, Nelson, Everette Jacob Remington
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10336457/
https://www.ncbi.nlm.nih.gov/pubmed/37449112
http://dx.doi.org/10.1016/j.heliyon.2023.e17553