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Repositioning of clinically approved drug Bazi Bushen capsule for treatment of Aizheimer's disease using network pharmacology approach and in vitro experimental validation

AIMS: To explore the new indications and key mechanism of Bazi Bushen capsule (BZBS) by network pharmacology and in vitro experiment. METHODS: The ingredients library of BZBS was constructed by retrieving multiple TCM databases. The potential target profiles of the components were predicted by targe...

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Detalles Bibliográficos
Autores principales: Wang, Tongxing, Chen, Meng, Li, Huixin, Ding, Guoyuan, Song, Yanfei, Hou, Bin, Yao, Bing, Wang, Zhixin, Hou, Yunlong, Liang, Junqing, Wei, Cong, Jia, Zhenhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10336525/
https://www.ncbi.nlm.nih.gov/pubmed/37449101
http://dx.doi.org/10.1016/j.heliyon.2023.e17603