Modeling Alzheimer’s disease related phenotypes in the Ts65Dn mouse: impact of age on Aβ, Tau, pTau, NfL, and behavior

INTRODUCTION: People with DS are highly predisposed to Alzheimer’s disease (AD) and demonstrate very similar clinical and pathological features. Ts65Dn mice are widely used and serve as the best-characterized animal model of DS. METHODS: We undertook studies to characterize age-related changes for A...

Descripción completa

Detalles Bibliográficos
Autores principales: Overk, Cassia, Fiorini, Emma, Babolin, Chiara, Vukicevic, Marija, Morici, Catherine, Madani, Rime, Eligert, Valerie, Kosco-Vilbois, Marie, Roberts, Amanda, Becker, Ann, Pfeifer, Andrea, Mobley, William C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10336548/
https://www.ncbi.nlm.nih.gov/pubmed/37449271
http://dx.doi.org/10.3389/fnins.2023.1202208

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10336548/
https://www.ncbi.nlm.nih.gov/pubmed/37449271
http://dx.doi.org/10.3389/fnins.2023.1202208

Ejemplares similares