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Modeling Alzheimer’s disease related phenotypes in the Ts65Dn mouse: impact of age on Aβ, Tau, pTau, NfL, and behavior

INTRODUCTION: People with DS are highly predisposed to Alzheimer’s disease (AD) and demonstrate very similar clinical and pathological features. Ts65Dn mice are widely used and serve as the best-characterized animal model of DS. METHODS: We undertook studies to characterize age-related changes for A...

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Detalles Bibliográficos
Autores principales:	Overk, Cassia, Fiorini, Emma, Babolin, Chiara, Vukicevic, Marija, Morici, Catherine, Madani, Rime, Eligert, Valerie, Kosco-Vilbois, Marie, Roberts, Amanda, Becker, Ann, Pfeifer, Andrea, Mobley, William C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10336548/ https://www.ncbi.nlm.nih.gov/pubmed/37449271 http://dx.doi.org/10.3389/fnins.2023.1202208

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