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Synthetic transformation of 6-Fluoroimidazo[1,2-a]Pyridine-3-carbaldehyde into 6-Fluoroimidazo[1,2-a]Pyridine-Oxazole Derivatives: In vitro urease inhibition and in silico study

PURPOSE: Ulcer is a serious disease that is caused due to different bacteria and over usage of various NSAIDs which caused to reduce the defensive system of stomach. Therefore, some novel series are needed to overcome these issues. METHODS: Oxazole-based imidazopyridine scaffolds (4a-p) were designe...

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Detalles Bibliográficos
Autores principales: Hussain, Rafaqat, Rehman, Wajid, Rahim, Fazal, Mahmoud, Ayman M., Alanazi, Mohammed M, Khan, Shoaib, Rasheed, Liaqat, Khan, Imran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10336670/
https://www.ncbi.nlm.nih.gov/pubmed/37448838
http://dx.doi.org/10.1016/j.jsps.2023.05.026