Cargando…
Bridging the diversity gap: Analytical and study design considerations for improving the accuracy of trans-ancestry genetic prediction
Genetic prediction of common complex disease risk is an essential component of precision medicine. Currently, genome-wide association studies (GWASs) are mostly composed of European-ancestry samples and resulting polygenic scores (PGSs) have been shown to poorly transfer to other ancestries partly d...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2023
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10336686/ https://www.ncbi.nlm.nih.gov/pubmed/37448981 http://dx.doi.org/10.1016/j.xhgg.2023.100214 |