Angiotensin II mediates hypertensive cardiac fibrosis via an Erbb4-IR-dependent mechanism

Transforming growth factor β (TGF-β)/Smad3 plays a vital role in hypertensive cardiac fibrosis. The long non-coding RNA (lncRNA) Erbb4-IR is a novel Smad3-dependent lncRNA that mediates kidney fibrosis. However, the role of Erbb4-IR in hypertensive heart disease remains unexplored and was investigat...

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Detalles Bibliográficos
Autores principales: Li, Jian-Chun, Jia, Jian, Dong, Li, Hu, Zhong-Jing, Huang, Xiao-Ru, Wang, Hong-Lian, Wang, Li, Yang, Si-Jin, Lan, Hui-Yao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10336735/
https://www.ncbi.nlm.nih.gov/pubmed/37449045
http://dx.doi.org/10.1016/j.omtn.2023.06.017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10336735/
https://www.ncbi.nlm.nih.gov/pubmed/37449045
http://dx.doi.org/10.1016/j.omtn.2023.06.017

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