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Angiotensin II mediates hypertensive cardiac fibrosis via an Erbb4-IR-dependent mechanism
Transforming growth factor β (TGF-β)/Smad3 plays a vital role in hypertensive cardiac fibrosis. The long non-coding RNA (lncRNA) Erbb4-IR is a novel Smad3-dependent lncRNA that mediates kidney fibrosis. However, the role of Erbb4-IR in hypertensive heart disease remains unexplored and was investigat...
Autores principales: | Li, Jian-Chun, Jia, Jian, Dong, Li, Hu, Zhong-Jing, Huang, Xiao-Ru, Wang, Hong-Lian, Wang, Li, Yang, Si-Jin, Lan, Hui-Yao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10336735/ https://www.ncbi.nlm.nih.gov/pubmed/37449045 http://dx.doi.org/10.1016/j.omtn.2023.06.017 |
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