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Biomimetic Electrospun Scaffold-Based In Vitro Model Resembling the Hallmarks of Human Myocardial Fibrotic Tissue

[Image: see text] Adverse remodeling post-myocardial infarction is hallmarked by the phenotypic change of cardiac fibroblasts (CFs) into myofibroblasts (MyoFs) and over-deposition of the fibrotic extracellular matrix (ECM) mainly composed by fibronectin and collagens, with the loss of tissue anisotr...

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Detalles Bibliográficos
Autores principales: Ruocco, Gerardina, Zoso, Alice, Mortati, Leonardo, Carmagnola, Irene, Chiono, Valeria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10336747/
https://www.ncbi.nlm.nih.gov/pubmed/37289177
http://dx.doi.org/10.1021/acsbiomaterials.3c00483