Highly protein-loaded melt extrudates produced by small-scale ram and twin-screw extrusion - evaluation of extrusion process design on protein stability by experimental and numerical approaches

Understanding of generation, extent and location of thermomechanical stress in small-scale (< 3 g) ram and twin-screw melt-extrusion is crucial for mechanistic correlations to the stability of protein particles (lysozyme and BSA) in PEG-matrices. The aim of the study was to apply and correlate ex...

Descripción completa

Detalles Bibliográficos
Autores principales: Dauer, Katharina, Kayser, Kevin, Ellwanger, Felix, Overbeck, Achim, Kwade, Arno, Karbstein, Heike P., Wagner, Karl G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10336796/
https://www.ncbi.nlm.nih.gov/pubmed/37448986
http://dx.doi.org/10.1016/j.ijpx.2023.100196

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10336796/
https://www.ncbi.nlm.nih.gov/pubmed/37448986
http://dx.doi.org/10.1016/j.ijpx.2023.100196

Ejemplares similares