Caspase-9 inhibition confers stronger neuronal and vascular protection compared to VEGF neutralization in a mouse model of retinal vein occlusion

PURPOSE: Retinal vein occlusion (RVO) is a sight-threatening condition typically treated with intravitreal injection of vascular endothelial growth factor (VEGF) antagonists. Treatment response to anti-VEGF therapies is highly variable, with poor visual outcomes and treatment response in patients wi...

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Detalles Bibliográficos
Autores principales: Avrutsky, Maria I., Chen, Claire W., Lawson, Jacqueline M., Snipas, Scott J., Salvesen, Guy S., Troy, Carol M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10336837/
https://www.ncbi.nlm.nih.gov/pubmed/37449272
http://dx.doi.org/10.3389/fnins.2023.1209527

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10336837/
https://www.ncbi.nlm.nih.gov/pubmed/37449272
http://dx.doi.org/10.3389/fnins.2023.1209527

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