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Unraveling the Reaction Mechanism of Russell’s Viper Venom Factor X Activator: A Paradigm for the Reactivity of Zinc Metalloproteinases?

[Image: see text] Snake venom metalloproteinases (SVMPs) are important drug targets against snakebite envenoming, the neglected tropical disease with the highest mortality worldwide. Here, we focus on Russell’s viper (Daboia russelii), one of the “big four” snakes of the Indian subcontinent that, to...

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Detalles Bibliográficos
Autores principales: Castro-Amorim, Juliana, Oliveira, Ana, Mukherjee, Ashis K., Ramos, Maria J., Fernandes, Pedro A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10336966/
https://www.ncbi.nlm.nih.gov/pubmed/37092784
http://dx.doi.org/10.1021/acs.jcim.2c01156