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Catalytic Atroposelective Aerobic Oxidation Approaches to Axially Chiral Molecules

[Image: see text] A copper and chiral nitroxide co-catalyzed aerobic enantioselective oxidation process has been developed that allows access to axially chiral molecules. Two complementary atroposelective approaches, oxidative kinetic resolution (OKR) and desymmetrization, were studied using ambient...

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Detalles Bibliográficos
Autores principales: Verdhi, Lenin Kumar, Ghosh, Asit, Fridman, Natalia, Szpilman, Alex M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10337035/
https://www.ncbi.nlm.nih.gov/pubmed/37322607
http://dx.doi.org/10.1021/acs.joc.3c00417